Detalhe da pesquisa
1.
Insights from a pharmacometric analysis of HDMTX in adults with cancer: Clinically relevant covariates for application in precision dosing.
Br J Clin Pharmacol
; 89(2): 660-671, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35998099
2.
Higher-order oligomerization promotes localization of SPOP to liquid nuclear speckles.
EMBO J
; 35(12): 1254-75, 2016 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27220849
3.
A fixation method to preserve cultured cell cytonemes facilitates mechanistic interrogation of morphogen transport.
Development
; 144(19): 3612-3624, 2017 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28827391
4.
Functional Divergence in the Role of N-Linked Glycosylation in Smoothened Signaling.
PLoS Genet
; 11(8): e1005473, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-26291458
5.
The small GTPase Rap1 is a modulator of Hedgehog signaling.
Dev Biol
; 409(1): 84-94, 2016 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26481064
6.
The extracellular loops of Smoothened play a regulatory role in control of Hedgehog pathway activation.
Development
; 139(3): 612-21, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-22223683
7.
Cleavage activates dispatched for Sonic Hedgehog ligand release.
Elife
; 72018 01 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-29359685
8.
Smoothened Regulation: A Tale of Two Signals.
Trends Pharmacol Sci
; 37(1): 62-72, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26432668
9.
Dataset for phenotypic classification of genetic modifiers of smoothened and Hedgehog.
Data Brief
; 7: 485-9, 2016 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-27014736
10.
Inducible protein traps with dominant phenotypes for functional analysis of the Drosophila genome.
Genetics
; 196(1): 91-105, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24172131
11.
The unfolded protein response selectively targets active smoothened mutants.
Mol Cell Biol
; 33(12): 2375-87, 2013 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-23572559
12.
Structural insights into the role of the Smoothened cysteine-rich domain in Hedgehog signalling.
Nat Commun
; 4: 2965, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-24351982
13.
Drosophila Pez acts in Hippo signaling to restrict intestinal stem cell proliferation.
Curr Biol
; 22(5): 389-96, 2012 Mar 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-22305752
14.
An Inv(16)(p13.3q24.3)-encoded CBFA2T3-GLIS2 fusion protein defines an aggressive subtype of pediatric acute megakaryoblastic leukemia.
Cancer Cell
; 22(5): 683-97, 2012 Nov 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-23153540